健康受試者的＂艱難抉擇＂

“A Difficult Choice" for Healthy Volunteers: A Case Study of a 2019-nCoV Vaccine Clinical Trial

Abstract

LANGUAGE NOTE | Document text in Chinese; abstract also in English.

以新冠疫苗I期試驗的健康受試者為研究對象，基於深度訪談和虛擬民族志研究方法，採用NVivo11軟體進行編碼分析，發現健康受試者的參與動機多為積極動機，在抉擇過程中曾面臨內外矛盾而深陷糾結與掙扎。文章歸納出新冠疫苗受試者抉擇過程不同階段的動機與行為特點，即：萌生想法——躍躍欲試的受試者；進退狐疑——踽踽獨行的受試者；備受煎熬——忐忑不安的受試者；解惑釋疑——篤定前行的受試者。旨在真實地還原健康受試者的抉擇過程，消除社會偏見，為健康受試者和I期試驗去除污名，提升公眾的認知，增强健康受試者的認同感和歸屬感。

Taking the Phase I trial of the 2019-nCoV vaccine as a case study, this paper examines the motivational and psychological development and behavioral patterns of healthy volunteers who participate in different phases of clinical trials for vaccines. The findings of a series of in-depth interviews and virtual ethnographical studies show that participation in a clinical trial such as that for the 2019-nCoV vaccine is a difficult choice for volunteers, as it entails exposure not only to medical risks but also to social prejudice. The paper provides a detailed account of how the volunteers for the Phase I 2019-nCoV vaccine trials made their choice to participate and how they overcame various doubts and fears to serve as responsible research partners.